SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.14A 3eeyA-2kc2A:
undetectable		 3eeyA-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.13A 3eeyB-2kc2A:
undetectable		 3eeyB-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.13A 3eeyC-2kc2A:
undetectable		 3eeyC-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.05A 3eeyE-2kc2A:
undetectable		 3eeyE-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.08A 3eeyF-2kc2A:
undetectable		 3eeyF-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.19A 3eeyH-2kc2A:
undetectable		 3eeyH-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.11A 3eeyI-2kc2A:
undetectable		 3eeyI-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 2kc2 TALIN-1
(Mus
musculus) 		5 / 12 THR A 114
ASP A 110
ILE A 119
GLY A 120
LEU A  88
 None
 1.09A 3eeyJ-2kc2A:
undetectable		 3eeyJ-2kc2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 2kc2 TALIN-1
(Mus
musculus) 		3 / 3 ARG A  91
GLU A 135
ARG A 194
 None
 0.86A 4mwvA-2kc2A:
undetectable		 4mwvA-2kc2A:
16.39