SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IG3_A_VIBA502_1 (THIAMIN PYROPHOSPHOKINASE)	2kc7	BFR218_PROTEIN (Bacteroides fragilis)	4 / 8	LEU A 20 ASN A 57 GLN A 52 ASP A 50	None	0.88A	1ig3A-2kc7A: undetectable 1ig3B-2kc7A: undetectable	1ig3A-2kc7A: 15.62 1ig3B-2kc7A: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5R_A_RBFA859_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	2kc7	BFR218_PROTEIN (Bacteroides fragilis)	5 / 11	LEU A 27 GLU A 24 TYR A 38 ALA A 44 TYR A 45	None	1.49A	1l5rA-2kc7A: undetectable	1l5rA-2kc7A: 6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA601_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	2kc7	BFR218_PROTEIN (Bacteroides fragilis)	4 / 7	GLY A 42 ASN A 43 ALA A 61 ILE A 11	None	0.77A	3a2qA-2kc7A: undetectable	3a2qA-2kc7A: 11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_2 (SCRFP-TAG,GP41)	2kc7	BFR218_PROTEIN (Bacteroides fragilis)	4 / 7	GLN A 52 LEU A 55 ALA A 61 LEU A 64	None	1.08A	5nwvA-2kc7A: undetectable	5nwvA-2kc7A: 22.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IG3_A_VIBA502_1","THIAMIN PYROPHOSPHOKINASE;THIAMIN PYROPHOSPHOKINASE","2kc7","BFR218_PROTEIN","Bacteroides fragilis",4,"LEU A  20;ASN A  57;GLN A  52;ASP A  50","None","0.88A","1ig3A-2kc7A:undetectable;1ig3B-2kc7A:undetectable","1ig3A-2kc7A:15.62;1ig3B-2kc7A:15.62"],["1L5R_A_RBFA859_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","2kc7","BFR218_PROTEIN","Bacteroides fragilis",5,"LEU A  27;GLU A  24;TYR A  38;ALA A  44;TYR A  45","None","1.49A","1l5rA-2kc7A:undetectable","1l5rA-2kc7A:6.92"],["3A2Q_A_ACAA601_1","6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE","2kc7","BFR218_PROTEIN","Bacteroides fragilis",4,"GLY A  42;ASN A  43;ALA A  61;ILE A  11","None","0.77A","3a2qA-2kc7A:undetectable","3a2qA-2kc7A:11.56"],["5NWV_A_ACAA18_2","SCRFP-TAG,GP41","2kc7","BFR218_PROTEIN","Bacteroides fragilis",4,"GLN A  52;LEU A  55;ALA A  61;LEU A  64","None","1.08A","5nwvA-2kc7A:undetectable","5nwvA-2kc7A:22.22"]]