SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kca'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	2kca	BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE (Bacillus phage SPP1)	5 / 11	ILE A 102 THR A 96 ASP A 99 VAL A 108 ILE A 43	None	1.27A	3kpcA-2kcaA: undetectable	3kpcA-2kcaA: 23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2kca	BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE (Bacillus phage SPP1)	4 / 5	VAL A 122 ILE A 102 PHE A 45 PHE A 66	None	1.05A	3owxB-2kcaA: undetectable	3owxB-2kcaA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1476_0 (MJ0495-LIKE PROTEIN)	2kca	BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE (Bacillus phage SPP1)	4 / 5	ILE A 43 ALA A 68 HIS A 71 ARG A 40	None	1.25A	4ac9B-2kcaA: undetectable 4ac9C-2kcaA: undetectable	4ac9B-2kcaA: 13.28 4ac9C-2kcaA: 13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1476_0 (TRANSLATION ELONGATION FACTOR SELB)	2kca	BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE (Bacillus phage SPP1)	4 / 5	ILE A 43 ALA A 68 HIS A 71 ARG A 40	None	1.26A	4acaB-2kcaA: 2.0 4acaC-2kcaA: undetectable	4acaB-2kcaA: 13.28 4acaC-2kcaA: 13.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KPC_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","2kca","BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE","Bacillus phage SPP1",5,"ILE A 102;THR A  96;ASP A  99;VAL A 108;ILE A  43","None","1.27A","3kpcA-2kcaA:undetectable","3kpcA-2kcaA:23.66"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2kca","BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE","Bacillus phage SPP1",4,"VAL A 122;ILE A 102;PHE A  45;PHE A  66","None","1.05A","3owxB-2kcaA:undetectable","3owxB-2kcaA:19.13"],["4AC9_C_DXCC1476_0","MJ0495-LIKE PROTEIN","2kca","BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE","Bacillus phage SPP1",4,"ILE A  43;ALA A  68;HIS A  71;ARG A  40","None","1.25A","4ac9B-2kcaA:undetectable;4ac9C-2kcaA:undetectable","4ac9B-2kcaA:13.28;4ac9C-2kcaA:13.28"],["4ACA_C_DXCC1476_0","TRANSLATION ELONGATION FACTOR SELB","2kca","BACTERIOPHAGE SPP1 COMPLETE NUCLEOTIDE SEQUENCE","Bacillus phage SPP1",4,"ILE A  43;ALA A  68;HIS A  71;ARG A  40","None","1.26A","4acaB-2kcaA:2.0;4acaC-2kcaA:undetectable","4acaB-2kcaA:13.28;4acaC-2kcaA:13.28"]]