SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN5_A_FUNA1356_1 (THYROXINE-BINDING GLOBULIN)	2kd0	LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105 (Arabidopsis thaliana)	5 / 11	SER A 23 LEU A 54 LEU A 37 LEU A 26 LEU A 67	None	0.98A	2xn5A-2kd0A: undetectable	2xn5A-2kd0A: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_2 (RIBOFLAVIN TRANSPORTER RIBU)	2kd0	LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105 (Arabidopsis thaliana)	3 / 3	LYS A 77 LEU A 37 ILE A 13	None	0.72A	5kc0A-2kd0A: undetectable	5kc0A-2kd0A: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFJ_A_SAMA501_0 (MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1)	2kd0	LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105 (Arabidopsis thaliana)	6 / 12	LEU A 67 ILE A 13 GLY A 73 LEU A 37 LEU A 41 LEU A 26	None	1.26A	5nfjA-2kd0A: undetectable	5nfjA-2kd0A: 13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCN_A_8LXA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2kd0	LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105 (Arabidopsis thaliana)	4 / 6	CYH A 32 SER A 29 HIS A 10 HIS A 7	None	1.47A	5ycnA-2kd0A: undetectable	5ycnA-2kd0A: 16.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XN5_A_FUNA1356_1","THYROXINE-BINDING GLOBULIN","2kd0","LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105","Arabidopsis thaliana",5,"SER A  23;LEU A  54;LEU A  37;LEU A  26;LEU A  67","None","0.98A","2xn5A-2kd0A:undetectable","2xn5A-2kd0A:15.33"],["5KC0_A_RBFA303_2","RIBOFLAVIN TRANSPORTER RIBU","2kd0","LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105","Arabidopsis thaliana",3,"LYS A  77;LEU A  37;ILE A  13","None","0.72A","5kc0A-2kd0A:undetectable","5kc0A-2kd0A:17.09"],["5NFJ_A_SAMA501_0","MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1","2kd0","LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105","Arabidopsis thaliana",6,"LEU A  67;ILE A  13;GLY A  73;LEU A  37;LEU A  41;LEU A  26","None","1.26A","5nfjA-2kd0A:undetectable","5nfjA-2kd0A:13.24"],["5YCN_A_8LXA501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2kd0","LRR REPEATS AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN AT2G30105","Arabidopsis thaliana",4,"CYH A  32;SER A  29;HIS A  10;HIS A   7","None","1.47A","5ycnA-2kd0A:undetectable","5ycnA-2kd0A:16.33"]]