SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 7 HIS A  86
TYR A  11
TYR A   8
LEU A  48
 None
 1.12A 1qzrA-2kd1A:
undetectable		 1qzrA-2kd1A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 4 GLN A  26
THR A  27
GLU A 112
HIS A 115
 None
 1.43A 3g1uD-2kd1A:
undetectable		 3g1uD-2kd1A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 5 GLN A  26
THR A  27
GLU A 112
HIS A 115
 None
 1.43A 3glqB-2kd1A:
undetectable		 3glqB-2kd1A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 5 GLN A  26
THR A  27
GLU A 112
HIS A 115
 None
 1.42A 3n58A-2kd1A:
undetectable		 3n58A-2kd1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 5 GLN A  26
THR A  27
GLU A 112
HIS A 115
 None
 1.41A 3n58C-2kd1A:
undetectable		 3n58C-2kd1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		4 / 4 GLN A  26
THR A  27
GLU A 112
HIS A 115
 None
 1.43A 3n58D-2kd1A:
undetectable		 3n58D-2kd1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2kd1 DNA
INTEGRATION/RECOMBIN
ATION/INVERTION
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A  46
TYR A  59
SER A  42
LEU A  43
LEU A  84
 None
 1.48A 4qztC-2kd1A:
undetectable		 4qztC-2kd1A:
23.08