SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 130
THR A  98
GLU A  87
 None
 0.79A 2zifB-2kd7A:
undetectable		 2zifB-2kd7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 105
ASN A 134
ALA A 138
LEU A 126
 None
 0.94A 4ejgA-2kd7A:
undetectable		 4ejgA-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 105
ASN A 134
ALA A 138
LEU A 126
 None
 0.90A 4ejgB-2kd7A:
undetectable		 4ejgB-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 105
ALA A 138
LEU A  33
LEU A 126
 None
 0.89A 4ejgC-2kd7A:
undetectable		 4ejgC-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 105
ASN A 134
ALA A 138
LEU A 126
 None
 0.92A 4ejgC-2kd7A:
undetectable		 4ejgC-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 105
ASN A 134
ALA A 138
LEU A  33
 None
 0.93A 4ejgD-2kd7A:
undetectable		 4ejgD-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A  55
THR A 127
THR A  16
 None
 0.83A 5aoxB-2kd7A:
undetectable		 5aoxB-2kd7A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2kd7 PUTATIVE CHITOBIASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A  76
ASP A 109
ARG A  77
GLY A  78
 None
 0.84A 5cdnA-2kd7A:
undetectable
5cdnB-2kd7A:
undetectable		 5cdnA-2kd7A:
15.22
5cdnB-2kd7A:
18.59