SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO5_A_CHDA131_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	2kdk	ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2 (Homo sapiens)	5 / 12	ILE A 340 ILE A 414 LEU A 348 CYH A 353 PHE A 386	None	1.14A	2qo5A-2kdkA: undetectable	2qo5A-2kdkA: 23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y00_A_Y00A601_2 (BETA-1 ADRENERGIC RECEPTOR)	2kdk	ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2 (Homo sapiens)	4 / 4	VAL A 331 PHE A 403 VAL A 372 TRP A 400	None	1.25A	2y00A-2kdkA: undetectable	2y00A-2kdkA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_B_SAMB500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	2kdk	ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	HIS A 369 SER A 398 ASN A 364	None	0.82A	3s8pB-2kdkA: undetectable	3s8pB-2kdkA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CPR_B_SAMB402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	2kdk	ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	HIS A 369 SER A 398 ASN A 364	None	0.84A	5cprB-2kdkA: undetectable	5cprB-2kdkA: 17.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QO5_A_CHDA131_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","2kdk","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2","Homo sapiens",5,"ILE A 340;ILE A 414;LEU A 348;CYH A 353;PHE A 386","None","1.14A","2qo5A-2kdkA:undetectable","2qo5A-2kdkA:23.94"],["2Y00_A_Y00A601_2","BETA-1 ADRENERGIC RECEPTOR","2kdk","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2","Homo sapiens",4,"VAL A 331;PHE A 403;VAL A 372;TRP A 400","None","1.25A","2y00A-2kdkA:undetectable","2y00A-2kdkA:17.03"],["3S8P_B_SAMB500_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","2kdk","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2","Homo sapiens",3,"HIS A 369;SER A 398;ASN A 364","None","0.82A","3s8pB-2kdkA:undetectable","3s8pB-2kdkA:16.67"],["5CPR_B_SAMB402_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","2kdk","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2","Homo sapiens",3,"HIS A 369;SER A 398;ASN A 364","None","0.84A","5cprB-2kdkA:undetectable","5cprB-2kdkA:17.22"]]