SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2keb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 2keb DNA POLYMERASE
SUBUNIT ALPHA B
(Homo
sapiens) 		3 / 3 VAL A  28
GLU A  25
GLU A  29
 None
 0.77A 2nv4A-2kebA:
undetectable		 2nv4A-2kebA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2keb DNA POLYMERASE
SUBUNIT ALPHA B
(Homo
sapiens) 		4 / 7 LEU A   8
LEU A  12
GLU A  29
LEU A  27
 None
 0.81A 4wg0L-2kebA:
undetectable
4wg0M-2kebA:
undetectable		 4wg0L-2kebA:
7.92
4wg0M-2kebA:
7.92