SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ker'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		4 / 6 GLY A  61
ASP A  60
ARG A  17
GLY A  56
 None
 0.92A 5cdnR-2kerA:
undetectable
5cdnS-2kerA:
undetectable		 5cdnR-2kerA:
7.96
5cdnS-2kerA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		5 / 12 ALA A  41
ASP A  20
PHE A  54
GLY A  56
TYR A  63
 None
 1.00A 5hfjB-2kerA:
undetectable		 5hfjB-2kerA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		5 / 12 ALA A  41
ASP A  20
PHE A  54
GLY A  56
TYR A  63
 None
 0.95A 5hfjD-2kerA:
undetectable		 5hfjD-2kerA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		5 / 12 ALA A  41
ASP A  20
PHE A  54
GLY A  56
TYR A  63
 None
 0.94A 5hfjE-2kerA:
undetectable		 5hfjE-2kerA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		5 / 12 ALA A  41
ASP A  20
PHE A  54
GLY A  56
TYR A  63
 None
 0.92A 5hfjG-2kerA:
undetectable		 5hfjG-2kerA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ker ALPHA-AMYLASE
INHIBITOR Z-2685
(Streptomyces
parvulus) 		5 / 12 ALA A  41
ASP A  20
PHE A  54
GLY A  56
TYR A  63
 None
 0.98A 5hfjH-2kerA:
undetectable		 5hfjH-2kerA:
17.00