SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 VAL A  46
GLY A  47
ALA A 107
LEU A 108
 None
 0.67A 1e7bB-2kfgA:
undetectable		 1e7bB-2kfgA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A 102
ASP A  54
ASN A  64
 None
 0.76A 2bm9D-2kfgA:
undetectable		 2bm9D-2kfgA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_B_CHDB1_0
(FERROCHELATASE)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 PRO A 132
SER A 134
VAL A  46
GLY A  47
TRP A  44
 None
 1.11A 2qd2B-2kfgA:
0.8		 2qd2B-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 8 PRO A 132
SER A 134
VAL A  46
GLY A  47
TRP A  44
 None
 1.17A 2qd3A-2kfgA:
undetectable		 2qd3A-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 132
SER A 134
VAL A  46
GLY A  47
 None
 0.60A 2qd5A-2kfgA:
undetectable		 2qd5A-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 132
SER A 134
VAL A  46
GLY A  47
 None
 0.52A 2qd5B-2kfgA:
undetectable		 2qd5B-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 PRO A 132
SER A 134
VAL A  46
TRP A  44
 None
 1.45A 4kmmA-2kfgA:
undetectable		 4kmmA-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2kfg EH DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 132
SER A 134
VAL A  46
GLY A  47
 None
 0.61A 4mk4A-2kfgA:
undetectable		 4mk4A-2kfgA:
13.91