SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 2kg4 GROWTH ARREST AND
DNA-DAMAGE-INDUCIBLE
PROTEIN GADD45 ALPHA
(Homo
sapiens) 		3 / 3 ASP A  68
ILE A  78
VAL A  92
 None
 0.66A 2avvD-2kg4A:
undetectable		 2avvD-2kg4A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 2kg4 GROWTH ARREST AND
DNA-DAMAGE-INDUCIBLE
PROTEIN GADD45 ALPHA
(Homo
sapiens) 		4 / 4 LEU A 162
GLY A  20
LEU A  23
GLU A  24
 None
 0.88A 3tgvB-2kg4A:
undetectable		 3tgvB-2kg4A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2kg4 GROWTH ARREST AND
DNA-DAMAGE-INDUCIBLE
PROTEIN GADD45 ALPHA
(Homo
sapiens) 		4 / 6 PHE A  75
ASP A  62
LEU A  71
HIS A 123
 None
 1.26A 4paeA-2kg4A:
undetectable		 4paeA-2kg4A:
11.84