SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2kgl MESODERM DEVELOPMENT
CANDIDATE 2
(Mus
musculus) 		4 / 7 GLY A  84
ASP A  37
ILE A  38
GLN A  31
 None
 0.79A 3fi0P-2kglA:
undetectable		 3fi0P-2kglA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 2kgl MESODERM DEVELOPMENT
CANDIDATE 2
(Mus
musculus) 		5 / 12 LEU A 102
GLY A 100
LYS A  72
GLU A  64
LEU A  67
 None
 1.31A 5nwvA-2kglA:
undetectable		 5nwvA-2kglA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2kgl MESODERM DEVELOPMENT
CANDIDATE 2
(Mus
musculus) 		3 / 3 PHE A 112
ARG A 111
GLN A 110
 None
 1.11A 6g1pB-2kglA:
undetectable		 6g1pB-2kglA:
18.62