SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kgw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 2kgw OUTER MEMBRANE
PROTEIN A
(Mycobacterium
tuberculosis) 		5 / 10 ASN A 263
GLY A 259
ARG A 277
ASN A 318
GLY A 299
 None
 1.09A 1ho5B-2kgwA:
undetectable		 1ho5B-2kgwA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 2kgw OUTER MEMBRANE
PROTEIN A
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 224
GLY A 226
LEU A 232
SER A 231
ASP A 236
 None
 1.41A 3pfgA-2kgwA:
undetectable		 3pfgA-2kgwA:
21.46