SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2khd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_B_SALB503_1 (SALICYLIC ACID-BINDING PROTEIN 2)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	5 / 10	ALA A 78 LEU A 76 PHE A 80 PHE A 91 LEU A 48	None	1.33A	1y7iB-2khdA: undetectable	1y7iB-2khdA: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DQR_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 7	PHE A 80 GLU A 87 VAL A 58 VAL A 62	None	1.28A	3dqrA-2khdA: undetectable 3dqrB-2khdA: undetectable	3dqrA-2khdA: 14.80 3dqrB-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX5_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 7	PHE A 80 GLU A 87 VAL A 58 VAL A 62	None	1.31A	3jx5A-2khdA: undetectable 3jx5B-2khdA: undetectable	3jx5A-2khdA: 14.80 3jx5B-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N61_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 6	VAL A 58 VAL A 62 PHE A 80 GLU A 87	None	1.34A	3n61A-2khdA: undetectable 3n61B-2khdA: undetectable	3n61A-2khdA: 14.80 3n61B-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 7	PHE A 80 GLU A 87 VAL A 58 VAL A 62	None	1.32A	3nlpA-2khdA: undetectable 3nlpB-2khdA: undetectable	3nlpA-2khdA: 14.80 3nlpB-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADE_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 7	PHE A 80 GLU A 87 VAL A 58 VAL A 62	None	1.32A	5adeA-2khdA: undetectable 5adeB-2khdA: undetectable	5adeA-2khdA: 14.80 5adeB-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0P_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	4 / 7	PHE A 80 GLU A 87 VAL A 58 VAL A 62	None	1.33A	5g0pA-2khdA: undetectable 5g0pB-2khdA: undetectable	5g0pA-2khdA: 14.80 5g0pB-2khdA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9Y_A_ACTA412_0 (UNCHARACTERIZED PROTEIN KDOO)	2khd	UNCHARACTERIZED PROTEIN VC_A0919 (Vibrio cholerae)	3 / 3	ARG A 96 PHE A 37 ARG A 100	None	1.18A	5y9yA-2khdA: undetectable	5y9yA-2khdA: 17.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_B_SALB503_1","SALICYLIC ACID-BINDING PROTEIN 2","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",5,"ALA A  78;LEU A  76;PHE A  80;PHE A  91;LEU A  48","None","1.33A","1y7iB-2khdA:undetectable","1y7iB-2khdA:20.15"],["3DQR_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"PHE A  80;GLU A  87;VAL A  58;VAL A  62","None","1.28A","3dqrA-2khdA:undetectable;3dqrB-2khdA:undetectable","3dqrA-2khdA:14.80;3dqrB-2khdA:14.80"],["3JX5_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"PHE A  80;GLU A  87;VAL A  58;VAL A  62","None","1.31A","3jx5A-2khdA:undetectable;3jx5B-2khdA:undetectable","3jx5A-2khdA:14.80;3jx5B-2khdA:14.80"],["3N61_A_H4BA760_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"VAL A  58;VAL A  62;PHE A  80;GLU A  87","None","1.34A","3n61A-2khdA:undetectable;3n61B-2khdA:undetectable","3n61A-2khdA:14.80;3n61B-2khdA:14.80"],["3NLP_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"PHE A  80;GLU A  87;VAL A  58;VAL A  62","None","1.32A","3nlpA-2khdA:undetectable;3nlpB-2khdA:undetectable","3nlpA-2khdA:14.80;3nlpB-2khdA:14.80"],["5ADE_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"PHE A  80;GLU A  87;VAL A  58;VAL A  62","None","1.32A","5adeA-2khdA:undetectable;5adeB-2khdA:undetectable","5adeA-2khdA:14.80;5adeB-2khdA:14.80"],["5G0P_B_H4BB760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",4,"PHE A  80;GLU A  87;VAL A  58;VAL A  62","None","1.33A","5g0pA-2khdA:undetectable;5g0pB-2khdA:undetectable","5g0pA-2khdA:14.80;5g0pB-2khdA:14.80"],["5Y9Y_A_ACTA412_0","UNCHARACTERIZED PROTEIN KDOO","2khd","UNCHARACTERIZED PROTEIN VC_A0919","Vibrio cholerae",3,"ARG A  96;PHE A  37;ARG A 100","None","1.18A","5y9yA-2khdA:undetectable","5y9yA-2khdA:17.61"]]