SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2khe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 9 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.27A 2f78A-2kheA:
undetectable		 2f78A-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 9 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.28A 2f78B-2kheA:
undetectable		 2f78B-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 9 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.24A 2f7aA-2kheA:
undetectable		 2f7aA-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 9 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.33A 2f7aB-2kheA:
undetectable		 2f7aB-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 10 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.28A 2f8dA-2kheA:
undetectable		 2f8dA-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		6 / 10 LEU A  47
LEU A  52
PHE A  55
LEU A  79
ARG A  80
ILE A  66
 None
 1.26A 2f8dB-2kheA:
undetectable		 2f8dB-2kheA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2khe TOXIN-LIKE PROTEIN
(Thermus
thermophilus) 		4 / 8 LEU A  65
VAL A  87
TYR A  63
LEU A  15
 None
 1.06A 4q0bA-2kheA:
undetectable		 4q0bA-2kheA:
9.35