SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2khq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU9_B_SPMB700_1 (POLYAMINE OXIDASE)	2khq	INTEGRASE (Staphylococcus saprophyticus)	4 / 7	TYR A 28 TYR A 59 PHE A 55 TYR A 52	None	1.29A	3ku9B-2khqA: 2.4	3ku9B-2khqA: 13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_A_ZPCA1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2khq	INTEGRASE (Staphylococcus saprophyticus)	4 / 7	ILE A 47 GLU A 51 PHE A 55 HIS A 41	None	0.94A	4a97A-2khqA: undetectable	4a97A-2khqA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	2khq	INTEGRASE (Staphylococcus saprophyticus)	4 / 7	TYR A 7 LEU A 44 ASN A 91 TYR A 52	None	1.35A	4f8yC-2khqA: undetectable 4f8yD-2khqA: undetectable	4f8yC-2khqA: 22.45 4f8yD-2khqA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEO_A_VDYA206_1 (CDL2.3A)	2khq	INTEGRASE (Staphylococcus saprophyticus)	5 / 12	LEU A 44 PHE A 4 LEU A 71 LEU A 56 PHE A 79	None	1.38A	5ieoA-2khqA: undetectable	5ieoA-2khqA: 26.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KU9_B_SPMB700_1","POLYAMINE OXIDASE","2khq","INTEGRASE","Staphylococcus saprophyticus",4,"TYR A  28;TYR A  59;PHE A  55;TYR A  52","None","1.29A","3ku9B-2khqA:2.4","3ku9B-2khqA:13.12"],["4A97_A_ZPCA1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL","2khq","INTEGRASE","Staphylococcus saprophyticus",4,"ILE A  47;GLU A  51;PHE A  55;HIS A  41","None","0.94A","4a97A-2khqA:undetectable","4a97A-2khqA:16.67"],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","2khq","INTEGRASE","Staphylococcus saprophyticus",4,"TYR A   7;LEU A  44;ASN A  91;TYR A  52","None","1.35A","4f8yC-2khqA:undetectable;4f8yD-2khqA:undetectable","4f8yC-2khqA:22.45;4f8yD-2khqA:22.45"],["5IEO_A_VDYA206_1","CDL2.3A","2khq","INTEGRASE","Staphylococcus saprophyticus",5,"LEU A  44;PHE A   4;LEU A  71;LEU A  56;PHE A  79","None","1.38A","5ieoA-2khqA:undetectable","5ieoA-2khqA:26.76"]]