SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2khz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		4 / 8 ALA A  97
LEU A  94
GLY A  91
GLY A  16
 None
 0.80A 1rukH-2khzA:
undetectable
1rukL-2khzA:
undetectable		 1rukH-2khzA:
20.09
1rukL-2khzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		4 / 8 TYR A  28
PHE A  14
ALA A  49
HIS A  45
 None
 1.07A 1x8vA-2khzA:
undetectable		 1x8vA-2khzA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		4 / 8 LEU A 143
ARG A 109
VAL A  90
GLY A  16
 None
 0.98A 2po5B-2khzA:
4.0		 2po5B-2khzA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		3 / 3 GLU A 140
LEU A 143
ASP A 144
 None
 0.47A 3ko0A-2khzA:
undetectable		 3ko0A-2khzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		3 / 3 GLU A 140
LEU A 143
ASP A 144
 None
 0.40A 3ko0T-2khzA:
undetectable		 3ko0T-2khzA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		5 / 6 LEU A  94
GLY A  91
VAL A  90
ALA A  81
LEU A 116
 None
 1.03A 4o0wA-2khzA:
undetectable		 4o0wA-2khzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		5 / 12 GLU A  44
GLU A  50
GLY A  16
ALA A  81
PHE A  14
 None
 1.21A 4retC-2khzA:
2.5		 4retC-2khzA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		5 / 11 ARG A 109
GLY A  16
SER A  87
ARG A 114
SER A 112
 None
 1.15A 4zbqA-2khzA:
undetectable		 4zbqA-2khzA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2khz C-MYC-RESPONSIVE
PROTEIN RCL
(Rattus
norvegicus) 		3 / 3 ARG A  34
PHE A 108
LEU A 105
 None
 0.73A 5veuA-2khzA:
undetectable		 5veuA-2khzA:
14.65