SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kii'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_0 (WNT INHIBITORY FACTOR 1)	2kii	PUTATIVE UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	5 / 12	ILE A 176 LEU A 130 ILE A 159 ILE A 98 PHE A 91	None None None HEM A 182 (-4.0A) None	0.95A	2ygnA-2kiiA: undetectable	2ygnA-2kiiA: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUB_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	2kii	PUTATIVE UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	3 / 3	TYR A 132 ARG A 131 HIS A 117	HEM A 182 (-4.3A) None None	1.14A	4fubA-2kiiA: undetectable	4fubA-2kiiA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WCX_C_SAMC503_0 (BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED)	2kii	PUTATIVE UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	5 / 12	TYR A 36 GLU A 46 PHE A 69 LEU A 73 LEU A 77	None None None None HEM A 182 ( 2.9A)	1.22A	4wcxC-2kiiA: undetectable	4wcxC-2kiiA: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Y_D_9CRD501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2kii	PUTATIVE UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	3 / 3	ASN A 7 VAL A 106 HIS A 81	None HEM A 182 (-4.0A) HEM A 182 (-2.9A)	0.75A	6a5yD-2kiiA: undetectable	6a5yD-2kiiA: 23.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGN_A_PCFA1179_0","WNT INHIBITORY FACTOR 1","2kii","PUTATIVE UNCHARACTERIZED PROTEIN","Shewanella oneidensis",5,"ILE A 176;LEU A 130;ILE A 159;ILE A  98;PHE A  91","None;None;None;HEM A 182 (-4.0A);None","0.95A","2ygnA-2kiiA:undetectable","2ygnA-2kiiA:21.81"],["4FUB_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","2kii","PUTATIVE UNCHARACTERIZED PROTEIN","Shewanella oneidensis",3,"TYR A 132;ARG A 131;HIS A 117","HEM A 182 (-4.3A);None;None","1.14A","4fubA-2kiiA:undetectable","4fubA-2kiiA:23.17"],["4WCX_C_SAMC503_0","BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED","2kii","PUTATIVE UNCHARACTERIZED PROTEIN","Shewanella oneidensis",5,"TYR A  36;GLU A  46;PHE A  69;LEU A  73;LEU A  77","None;None;None;None;HEM A 182 ( 2.9A)","1.22A","4wcxC-2kiiA:undetectable","4wcxC-2kiiA:16.35"],["6A5Y_D_9CRD501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2kii","PUTATIVE UNCHARACTERIZED PROTEIN","Shewanella oneidensis",3,"ASN A   7;VAL A 106;HIS A  81","None;HEM A 182 (-4.0A);HEM A 182 (-2.9A)","0.75A","6a5yD-2kiiA:undetectable","6a5yD-2kiiA:23.45"]]