SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OTH_A_NIMA300_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	2kij	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 5	LEU A 7 ALA A 86 ILE A 85 SER A 88	None	0.98A	2othA-2kijA: undetectable	2othA-2kijA: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRH_A_NIOA200_1 (PROTEIN HP0721)	2kij	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 7	GLY A 40 ILE A 17 THR A 19 GLN A 38	None	1.02A	2xrhA-2kijA: undetectable	2xrhA-2kijA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PP1_A_ACTA590_0 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	2kij	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 5	GLU A 59 LEU A 95 HIS A 61 GLY A 93	None	1.29A	3pp1A-2kijA: undetectable	3pp1A-2kijA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L78_A_ACTA1327_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	2kij	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 4	VAL A 32 THR A 16 GLU A 30 GLU A 29	None	1.26A	4l78A-2kijA: undetectable	4l78A-2kijA: 7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OJB_A_198A1001_2 (ANDROGEN RECEPTOR)	2kij	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 7	LEU A 108 ILE A 43 ILE A 97 VAL A 45	None	0.85A	4ojbA-2kijA: undetectable	4ojbA-2kijA: 17.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OTH_A_NIMA300_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","2kij","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"LEU A   7;ALA A  86;ILE A  85;SER A  88","None","0.98A","2othA-2kijA:undetectable","2othA-2kijA:17.69"],["2XRH_A_NIOA200_1","PROTEIN HP0721","2kij","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"GLY A  40;ILE A  17;THR A  19;GLN A  38","None","1.02A","2xrhA-2kijA:undetectable","2xrhA-2kijA:22.40"],["3PP1_A_ACTA590_0","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","2kij","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"GLU A  59;LEU A  95;HIS A  61;GLY A  93","None","1.29A","3pp1A-2kijA:undetectable","3pp1A-2kijA:18.79"],["4L78_A_ACTA1327_0","PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE","2kij","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"VAL A  32;THR A  16;GLU A  30;GLU A  29","None","1.26A","4l78A-2kijA:undetectable","4l78A-2kijA:7.46"],["4OJB_A_198A1001_2","ANDROGEN RECEPTOR","2kij","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"LEU A 108;ILE A  43;ILE A  97;VAL A  45","None","0.85A","4ojbA-2kijA:undetectable","4ojbA-2kijA:17.51"]]