SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		4 / 7 ARG A  65
ILE A  38
PHE A  62
GLU A  57
 None
 1.41A 2nsiC-2kj8A:
1.7
2nsiD-2kj8A:
undetectable		 2nsiC-2kj8A:
14.82
2nsiD-2kj8A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		4 / 7 ILE A  10
TYR A  11
PHE A  34
ASP A  35
 None
 1.15A 2qebA-2kj8A:
undetectable		 2qebA-2kj8A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		4 / 5 PRO A  40
ILE A  38
ARG A  61
ASP A  37
 None
 1.17A 2rhmB-2kj8A:
undetectable		 2rhmB-2kj8A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		4 / 7 VAL A  58
PHE A  34
VAL A  81
PHE A  82
 None
 0.97A 3zjqA-2kj8A:
undetectable		 3zjqA-2kj8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		4 / 7 ARG A  65
ILE A  38
PHE A  62
GLU A  57
 None
 1.35A 4nosC-2kj8A:
undetectable
4nosD-2kj8A:
undetectable		 4nosC-2kj8A:
14.39
4nosD-2kj8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		3 / 3 MET A  33
GLU A  69
ARG A  70
 None
 1.10A 5tjyA-2kj8A:
undetectable		 5tjyA-2kj8A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 2kj8 PUTATIVE PROPHAGE
CPS-53 INTEGRASE
(Escherichia
coli) 		5 / 9 ILE A  38
ILE A  41
GLU A  80
ILE A  42
MET A 103
 None
 1.24A 6hloA-2kj8A:
undetectable		 6hloA-2kj8A:
13.09