SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1
(Homo
sapiens) 		4 / 8 LEU A  26
ARG A  56
SER A  49
VAL A  89
 None
 1.21A 2qd2A-2kjdA:
undetectable		 2qd2A-2kjdA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1
(Homo
sapiens) 		3 / 3 CYH A 100
PHE A  97
PHE A  96
 None
 0.77A 3cr5X-2kjdA:
undetectable		 3cr5X-2kjdA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1
(Homo
sapiens) 		4 / 5 GLU A  66
ARG A  56
PRO A 104
SER A 105
 None
 1.30A 4k17B-2kjdA:
undetectable		 4k17B-2kjdA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1
(Homo
sapiens) 		4 / 7 LEU A  26
ARG A  56
SER A  49
VAL A  89
 None
 1.24A 4klrA-2kjdA:
undetectable		 4klrA-2kjdA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1
(Homo
sapiens) 		4 / 8 ASP A  29
HIS A  27
ASP A  94
GLU A  95
 None
 1.21A 6mn4A-2kjdA:
undetectable		 6mn4A-2kjdA:
21.52