SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		4 / 8 LEU A  12
VAL A  82
LEU A  28
VAL A  24
 None
 0.94A 2bdmA-2kjgA:
undetectable		 2bdmA-2kjgA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		5 / 12 ASP A  29
LEU A  28
LEU A  70
LEU A  35
ILE A  31
 None
 1.06A 4x1fA-2kjgA:
undetectable		 4x1fA-2kjgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		5 / 12 ASP A  29
LEU A  28
LEU A  70
LEU A  35
ILE A  31
 None
 1.07A 4x1gA-2kjgA:
undetectable		 4x1gA-2kjgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		5 / 9 ILE A  56
GLU A  61
LEU A  12
MET A  65
ILE A  66
 None
 1.39A 5mzpA-2kjgA:
undetectable		 5mzpA-2kjgA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		3 / 3 LEU A  23
GLN A  26
LYS A  58
 None
 0.92A 6exiB-2kjgA:
undetectable		 6exiB-2kjgA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2kjg ARCHAEAL PROTEIN
SSO6904
(Sulfolobus
solfataricus) 		3 / 3 LEU A  23
GLN A  26
LYS A  58
 None
 0.90A 6exiA-2kjgA:
undetectable		 6exiA-2kjgA:
24.49