SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		4 / 5 ALA A  72
ALA A  81
ALA A  84
VAL A  57
 None
 0.83A 2nyrB-2kjqA:
undetectable		 2nyrB-2kjqA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		5 / 12 GLY A  64
GLU A  85
TRP A  56
GLY A 116
ARG A 109
 None
 1.14A 3jzjA-2kjqA:
undetectable		 3jzjA-2kjqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		3 / 3 LEU A  53
TRP A  56
GLY A  36
 None
 0.74A 3l35A-2kjqA:
undetectable
3l35H-2kjqA:
undetectable		 3l35A-2kjqA:
14.58
3l35H-2kjqA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		3 / 3 LEU A  53
TRP A  56
GLY A  36
 None
 0.72A 3l35B-2kjqA:
undetectable
3l35K-2kjqA:
undetectable		 3l35B-2kjqA:
14.58
3l35K-2kjqA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		3 / 3 TYR A  29
HIS A  51
ARG A  32
 None
 0.75A 4e7bC-2kjqA:
undetectable		 4e7bC-2kjqA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		5 / 10 MET A 139
ALA A 140
GLU A 133
PHE A 107
LEU A 103
 None
 1.27A 4la0A-2kjqA:
undetectable		 4la0A-2kjqA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		5 / 9 MET A 139
ALA A 140
GLU A 133
PHE A 107
LEU A 103
 None
 1.25A 4la0B-2kjqA:
undetectable		 4la0B-2kjqA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 2kjq DNAA-RELATED PROTEIN
(Neisseria
meningitidis) 		4 / 5 SER A 113
GLY A 114
ARG A 109
GLU A  85
 None
 1.06A 4r82A-2kjqA:
undetectable
4r82B-2kjqA:
undetectable		 4r82A-2kjqA:
25.62
4r82B-2kjqA:
25.62