SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9N_A_CAMA1419_0 (CYTOCHROME P450)	2kjz	ATC0852 (Agrobacterium fabrum)	4 / 8	LEU A 9 LEU A 49 GLY A 48 VAL A 27	None	0.83A	4c9nA-2kjzA: undetectable	4c9nA-2kjzA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_E_CHDE104_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	2kjz	ATC0852 (Agrobacterium fabrum)	6 / 11	ALA A 69 LEU A 68 LEU A 47 ASN A 43 LEU A 41 LEU A 25	None	1.25A	4wg0C-2kjzA: undetectable 4wg0D-2kjzA: undetectable 4wg0E-2kjzA: undetectable	4wg0C-2kjzA: 7.46 4wg0D-2kjzA: 7.46 4wg0E-2kjzA: 7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE0_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2kjz	ATC0852 (Agrobacterium fabrum)	6 / 9	THR A 18 PHE A 39 GLY A 48 THR A 7 LEU A 68 LEU A 115	None	1.49A	4ze0A-2kjzA: undetectable	4ze0A-2kjzA: 12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HS1_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2kjz	ATC0852 (Agrobacterium fabrum)	5 / 8	PHE A 39 GLY A 48 THR A 7 LEU A 68 LEU A 115	None	1.30A	5hs1A-2kjzA: undetectable	5hs1A-2kjzA: 12.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4C9N_A_CAMA1419_0","CYTOCHROME P450","2kjz","ATC0852","Agrobacterium fabrum",4,"LEU A   9;LEU A  49;GLY A  48;VAL A  27","None","0.83A","4c9nA-2kjzA:undetectable","4c9nA-2kjzA:16.75"],["4WG0_E_CHDE104_0","NUCLEAR RECEPTOR COACTIVATOR 2","2kjz","ATC0852","Agrobacterium fabrum",6,"ALA A  69;LEU A  68;LEU A  47;ASN A  43;LEU A  41;LEU A  25","None","1.25A","4wg0C-2kjzA:undetectable;4wg0D-2kjzA:undetectable;4wg0E-2kjzA:undetectable","4wg0C-2kjzA:7.46;4wg0D-2kjzA:7.46;4wg0E-2kjzA:7.46"],["4ZE0_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2kjz","ATC0852","Agrobacterium fabrum",6,"THR A  18;PHE A  39;GLY A  48;THR A   7;LEU A  68;LEU A 115","None","1.49A","4ze0A-2kjzA:undetectable","4ze0A-2kjzA:12.62"],["5HS1_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2kjz","ATC0852","Agrobacterium fabrum",5,"PHE A  39;GLY A  48;THR A   7;LEU A  68;LEU A 115","None","1.30A","5hs1A-2kjzA:undetectable","5hs1A-2kjzA:12.74"]]