SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 8 LEU A  53
ILE A  97
LEU A  86
ILE A  83
 None
 0.90A 2azxA-2kk6A:
undetectable		 2azxA-2kk6A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 7 ARG A  42
SER A  44
ARG A  26
GLU A  50
 None
 1.16A 2c8aA-2kk6A:
undetectable		 2c8aA-2kk6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 6 ARG A  42
SER A  44
ARG A  26
GLU A  50
 None
 1.11A 2c8aC-2kk6A:
undetectable		 2c8aC-2kk6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 7 VAL A 103
SER A 101
ARG A  62
HIS A  63
 None
 0.92A 2f78A-2kk6A:
undetectable		 2f78A-2kk6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 6 VAL A 103
SER A 101
ARG A  62
HIS A  63
 None
 0.87A 2f8dA-2kk6A:
undetectable		 2f8dA-2kk6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 8 TYR A  51
GLY A  49
PRO A  48
GLU A  43
 None
 0.94A 2ys6A-2kk6A:
undetectable		 2ys6A-2kk6A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		4 / 8 LEU A  53
HIS A  21
LEU A  32
LEU A  33
 None
 0.91A 4l1xA-2kk6A:
undetectable		 4l1xA-2kk6A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER
(Homo
sapiens) 		3 / 3 LEU A  86
SER A  81
PHE A  80
 None
 0.63A 6fgcA-2kk6A:
undetectable		 6fgcA-2kk6A:
14.15