SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 7 LYS A 141
ARG A  62
GLY A  63
PRO A  64
 None
 1.25A 3ucbB-2kklA:
undetectable		 3ucbB-2kklA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 7 LYS A 141
ARG A 143
GLY A  63
PRO A  64
 None
 1.33A 3ucbB-2kklA:
undetectable		 3ucbB-2kklA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 6 GLY A 114
VAL A 113
ASP A 112
THR A 119
 None
 1.15A 3vqrA-2kklA:
undetectable		 3vqrA-2kklA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 5 GLY A 114
VAL A 113
ASP A 112
THR A 119
 None
 1.13A 3vqrB-2kklA:
undetectable		 3vqrB-2kklA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 6 LEU A  89
THR A  77
ALA A  79
SER A  95
 None
 0.86A 4pwjA-2kklA:
undetectable		 4pwjA-2kklA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 7 LEU A  89
THR A  77
ALA A  79
SER A  95
 None
 0.86A 4pwjB-2kklA:
undetectable		 4pwjB-2kklA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2kkl UNCHARACTERIZED
PROTEIN MB1858
(Mycobacterium
bovis) 		4 / 7 LEU A  89
THR A  77
ALA A  79
SER A  95
 None
 0.88A 5bojB-2kklA:
undetectable		 5bojB-2kklA:
18.18