SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kko'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_C_STRC3001_1 (MINERALOCORTICOID RECEPTOR)	2kko	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) (Mycobacterium bovis)	5 / 12	LEU A 28 LEU A 31 LEU A 34 ALA A 35 LEU A 89	None	1.10A	1ya3C-2kkoA: undetectable	1ya3C-2kkoA: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_D_VIVD301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2kko	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) (Mycobacterium bovis)	5 / 12	VAL A 15 LEU A 22 VAL A 93 LEU A 92 PHE A 90	None	1.25A	3w67D-2kkoA: undetectable	3w67D-2kkoA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2kko	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) (Mycobacterium bovis)	5 / 12	VAL A 15 LEU A 22 VAL A 93 LEU A 92 PHE A 90	None	1.26A	3w68C-2kkoA: undetectable	3w68C-2kkoA: 20.09