SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 TRP A 124
THR A 117
TYR A  88
 None
 1.13A 2a3aA-2kl2A:
undetectable		 2a3aA-2kl2A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 TRP A 124
THR A 117
TYR A  88
 None
 1.11A 2a3aB-2kl2A:
undetectable		 2a3aB-2kl2A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 TRP A 124
THR A 117
TYR A  88
 None
 1.14A 2a3bA-2kl2A:
undetectable		 2a3bA-2kl2A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A  53
HIS A  61
THR A  36
TYR A   7
THR A  64
 None
 1.01A 3thrA-2kl2A:
0.0
3thrB-2kl2A:
0.0
3thrC-2kl2A:
0.0
3thrD-2kl2A:
0.0		 3thrA-2kl2A:
19.33
3thrB-2kl2A:
19.33
3thrC-2kl2A:
19.33
3thrD-2kl2A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 GLY A 140
LEU A 141
HIS A 139
 None
 0.65A 5u63A-2kl2A:
undetectable		 5u63A-2kl2A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2kl2 AIG2-LIKE
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 GLY A 140
LEU A 141
HIS A 139
 None
 0.62A 5u63B-2kl2A:
undetectable		 5u63B-2kl2A:
17.39