SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 LEU A  94
GLY A  68
ILE A  37
LEU A  90
GLY A  92
GLY A  93
 None
 1.36A 1uakA-2kl3A:
undetectable		 1uakA-2kl3A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 LEU A  94
GLY A  68
ILE A  37
VAL A  64
LEU A  90
GLY A  93
 None
 1.11A 1uakA-2kl3A:
undetectable		 1uakA-2kl3A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 8 GLY A  93
GLY A  92
ALA A  95
ALA A  96
 None
 0.61A 2ha4A-2kl3A:
2.0		 2ha4A-2kl3A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 GLY A  93
GLY A  92
ALA A  95
ALA A  96
 None
 0.62A 2ha4B-2kl3A:
undetectable		 2ha4B-2kl3A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 GLY A  35
GLU A 105
THR A 104
 None
 0.46A 4kouA-2kl3A:
undetectable		 4kouA-2kl3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 8 HIS A  86
ASP A  61
SER A  88
SER A   5
 None
 1.20A 4kttA-2kl3A:
undetectable		 4kttA-2kl3A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 LEU A  94
GLY A  68
ILE A  37
LEU A  90
GLY A  92
GLY A  93
 None
 1.37A 5wyqB-2kl3A:
undetectable		 5wyqB-2kl3A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 LEU A  94
GLY A  68
ILE A  37
LEU A  90
GLY A  92
GLY A  93
 None
 1.40A 5zhmB-2kl3A:
undetectable		 5zhmB-2kl3A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2kl3 ALR3790 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 LEU A  94
GLY A  68
ILE A  37
VAL A  64
LEU A  90
GLY A  93
 None
 1.23A 5zhmB-2kl3A:
undetectable		 5zhmB-2kl3A:
22.91