SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		4 / 5 VAL A  50
GLY A  51
VAL A  96
TRP A  53
 None
 1.21A 1tkqB-2kl5A:
undetectable		 1tkqB-2kl5A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		4 / 6 ARG A  38
PHE A  35
ILE A  15
PHE A  20
 None
 1.00A 2qeiA-2kl5A:
undetectable		 2qeiA-2kl5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		6 / 12 LEU A  22
GLY A  29
ASP A  52
VAL A  50
ILE A  84
VAL A  23
 None
 1.42A 3jw2B-2kl5A:
undetectable		 3jw2B-2kl5A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		6 / 12 LEU A  22
GLY A  29
ASP A  52
VAL A  50
ILE A  84
VAL A  23
 None
 1.44A 3k4vB-2kl5A:
undetectable		 3k4vB-2kl5A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		6 / 12 LEU A  22
GLY A  29
ASP A  52
VAL A  50
ILE A  84
VAL A  23
 None
 1.41A 3tkwB-2kl5A:
undetectable		 3tkwB-2kl5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2kl5 UNCHARACTERIZED
PROTEIN YUTD
(Bacillus
subtilis) 		6 / 12 LEU A  22
GLY A  29
ASP A  52
VAL A  50
ILE A  84
VAL A  23
 None
 1.42A 4jecA-2kl5A:
undetectable		 4jecA-2kl5A:
21.10