SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2klx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 5 LEU A  22
LEU A  21
LEU A  81
LEU A  80
 None
 0.98A 2ab2B-2klxA:
undetectable		 2ab2B-2klxA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 6 ILE A   5
TYR A  29
ILE A  55
HIS A  61
 None
 1.12A 3eteA-2klxA:
undetectable
3eteE-2klxA:
undetectable		 3eteA-2klxA:
13.96
3eteE-2klxA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 5 ILE A   5
TYR A  29
ILE A  55
HIS A  61
 None
 1.12A 3eteB-2klxA:
undetectable
3eteC-2klxA:
undetectable		 3eteB-2klxA:
13.96
3eteC-2klxA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 7 ILE A  55
HIS A  61
ILE A   5
TYR A  29
 None
 1.12A 3eteD-2klxA:
undetectable
3eteF-2klxA:
undetectable		 3eteD-2klxA:
13.96
3eteF-2klxA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 8 ILE A   4
ASP A  83
GLN A  54
GLY A  63
 None
 0.71A 4ac9C-2klxA:
undetectable		 4ac9C-2klxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 8 ILE A   4
ASP A  83
GLN A  54
GLY A  63
 None
 0.72A 4acaC-2klxA:
undetectable		 4acaC-2klxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		4 / 8 ILE A   4
ASP A  83
GLN A  54
GLY A  63
 None
 0.72A 4acbC-2klxA:
undetectable		 4acbC-2klxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		3 / 3 ASP A  66
ARG A  17
TYR A  69
 None
 0.88A 5a7mA-2klxA:
undetectable		 5a7mA-2klxA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 2klx GLUTAREDOXIN
(Bartonella
henselae) 		3 / 3 ASP A  66
ARG A  17
TYR A  69
 None
 0.87A 5a7mB-2klxA:
undetectable		 5a7mB-2klxA:
8.48