SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 2kma TALIN 1
(Mus
musculus) 		3 / 3 ASP A  77
ASP A  69
ASP A  53
 None
 0.73A 1eizA-2kmaA:
undetectable		 1eizA-2kmaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 2kma TALIN 1
(Mus
musculus) 		3 / 3 ASP A  77
ASP A  69
ASP A  53
 None
 0.66A 1ej0A-2kmaA:
undetectable		 1ej0A-2kmaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2kma TALIN 1
(Mus
musculus) 		4 / 6 LEU A 133
LEU A 174
ILE A  90
GLU A 186
 None
 1.08A 1mt1A-2kmaA:
undetectable
1mt1F-2kmaA:
undetectable		 1mt1A-2kmaA:
14.12
1mt1F-2kmaA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2kma TALIN 1
(Mus
musculus) 		5 / 11 VAL A 102
LEU A  88
LEU A 193
VAL A 185
LEU A 180
 None
 1.10A 3zosA-2kmaA:
undetectable
3zosB-2kmaA:
undetectable		 3zosA-2kmaA:
21.24
3zosB-2kmaA:
21.24