SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2kmg KLCA
(Bordetella
pertussis) 		4 / 7 GLN A 103
ALA A  40
ARG A  33
GLU A 107
 None
 1.37A 1t9wA-2kmgA:
2.1		 1t9wA-2kmgA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2kmg KLCA
(Bordetella
pertussis) 		3 / 3 TYR A  25
GLY A  62
ASP A  61
 None
 0.68A 3ou6C-2kmgA:
undetectable		 3ou6C-2kmgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 2kmg KLCA
(Bordetella
pertussis) 		3 / 3 THR A 111
ASP A 112
ALA A 113
 None
 0.00A 5g5gB-2kmgA:
undetectable		 5g5gB-2kmgA:
20.00