SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UYU_B_CAMB1416_0 (CYTOCHROME P450-CAM)	2kmm	GUANOSINE-3',5'-BIS( DIPHOSPHATE) 3'-PYROPHOSPHOHYDROL ASE (Porphyromonas gingivalis)	4 / 8	LEU A 431 VAL A 421 THR A 423 VAL A 476	None	1.02A	1uyuB-2kmmA: undetectable	1uyuB-2kmmA: 10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZAX_A_CAMA422_0 (CYTOCHROME P450-CAM)	2kmm	GUANOSINE-3',5'-BIS( DIPHOSPHATE) 3'-PYROPHOSPHOHYDROL ASE (Porphyromonas gingivalis)	4 / 7	LEU A 431 VAL A 421 THR A 423 VAL A 476	None	1.06A	2zaxA-2kmmA: undetectable	2zaxA-2kmmA: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FWG_B_CAMB420_0 (CAMPHOR 5-MONOOXYGENASE)	2kmm	GUANOSINE-3',5'-BIS( DIPHOSPHATE) 3'-PYROPHOSPHOHYDROL ASE (Porphyromonas gingivalis)	4 / 7	LEU A 431 VAL A 421 THR A 423 VAL A 476	None	1.07A	3fwgB-2kmmA: undetectable	3fwgB-2kmmA: 11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM3_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	2kmm	GUANOSINE-3',5'-BIS( DIPHOSPHATE) 3'-PYROPHOSPHOHYDROL ASE (Porphyromonas gingivalis)	4 / 6	LEU A 444 SER A 443 PHE A 440 ASP A 439	None	1.06A	5om3A-2kmmA: undetectable 5om3B-2kmmA: undetectable	5om3A-2kmmA: 24.72 5om3B-2kmmA: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UYU_B_CAMB1416_0","CYTOCHROME P450-CAM","2kmm","GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE","Porphyromonas gingivalis",4,"LEU A 431;VAL A 421;THR A 423;VAL A 476","None","1.02A","1uyuB-2kmmA:undetectable","1uyuB-2kmmA:10.99"],["2ZAX_A_CAMA422_0","CYTOCHROME P450-CAM","2kmm","GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE","Porphyromonas gingivalis",4,"LEU A 431;VAL A 421;THR A 423;VAL A 476","None","1.06A","2zaxA-2kmmA:undetectable","2zaxA-2kmmA:11.24"],["3FWG_B_CAMB420_0","CAMPHOR 5-MONOOXYGENASE","2kmm","GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE","Porphyromonas gingivalis",4,"LEU A 431;VAL A 421;THR A 423;VAL A 476","None","1.07A","3fwgB-2kmmA:undetectable","3fwgB-2kmmA:11.27"],["5OM3_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","2kmm","GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE","Porphyromonas gingivalis",4,"LEU A 444;SER A 443;PHE A 440;ASP A 439","None","1.06A","5om3A-2kmmA:undetectable;5om3B-2kmmA:undetectable","5om3A-2kmmA:24.72;5om3B-2kmmA:18.18"]]