SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kmx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2kmx COPPER-TRANSPORTING
ATPASE 1
(Homo
sapiens) 		4 / 8 GLY A1078
THR A1079
ALA A1080
VAL A1218
 None
 0.63A 2a1hA-2kmxA:
undetectable
2a1hB-2kmxA:
undetectable		 2a1hA-2kmxA:
20.17
2a1hB-2kmxA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2kmx COPPER-TRANSPORTING
ATPASE 1
(Homo
sapiens) 		4 / 8 VAL A1218
GLY A1078
THR A1079
ALA A1080
 None
 0.67A 2a1hA-2kmxA:
undetectable
2a1hB-2kmxA:
undetectable		 2a1hA-2kmxA:
20.17
2a1hB-2kmxA:
20.17