SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		4 / 8 ILE A  26
LEU A  31
ALA A  54
VAL A  62
 None
None
None
CA  A 209 ( 4.5A)
 0.39A 1a29A-2kn2A:
11.3		 1a29A-2kn2A:
42.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 11 PHE A  18
ILE A  26
LEU A  31
LEU A  38
MET A  50
 None
 0.90A 1dtlA-2kn2A:
10.9		 1dtlA-2kn2A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 11 PHE A  18
ILE A  26
LEU A  31
MET A  35
LEU A  38
 None
 0.51A 1dtlA-2kn2A:
10.9		 1dtlA-2kn2A:
24.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2kn2 CALMODULIN
(Glycine
max) 		6 / 12 PHE A  18
ILE A  26
LEU A  31
MET A  35
LEU A  38
MET A  50
 None
 0.95A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2kn2 CALMODULIN
(Glycine
max) 		7 / 12 PHE A  18
ILE A  26
LEU A  31
MET A  35
MET A  50
ILE A  51
VAL A  62
 None
None
None
None
None
None
CA  A 209 ( 4.5A)
 0.98A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2kn2 CALMODULIN
(Glycine
max) 		7 / 12 PHE A  18
ILE A  26
LEU A  31
MET A  35
MET A  50
VAL A  62
MET A  71
 None
None
None
None
None
CA  A 209 ( 4.5A)
None
 0.98A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 8 ILE A  26
LEU A  31
MET A  35
ALA A  54
VAL A  62
 None
None
None
None
CA  A 209 ( 4.5A)
 0.58A 4rjdA-2kn2A:
11.3		 4rjdA-2kn2A:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 8 ILE A  26
LEU A  31
MET A  35
MET A  50
VAL A  62
 None
None
None
None
CA  A 209 ( 4.5A)
 1.08A 4rjdA-2kn2A:
11.3		 4rjdA-2kn2A:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 8 PHE A  18
ILE A  26
LEU A  31
ALA A  54
VAL A  62
 None
None
None
None
CA  A 209 ( 4.5A)
 0.37A 4rjdA-2kn2A:
11.3		 4rjdA-2kn2A:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 8 PHE A  18
ILE A  26
LEU A  31
MET A  50
VAL A  62
 None
None
None
None
CA  A 209 ( 4.5A)
 0.88A 4rjdA-2kn2A:
11.3		 4rjdA-2kn2A:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 7 PHE A  18
LEU A  31
MET A  35
ALA A  54
MET A  71
 None
 0.50A 4rjdB-2kn2A:
11.0		 4rjdB-2kn2A:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2kn2 CALMODULIN
(Glycine
max) 		5 / 7 PHE A  18
LEU A  31
MET A  35
MET A  50
ALA A  54
 None
 0.95A 4rjdB-2kn2A:
11.0		 4rjdB-2kn2A:
80.60