SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ko1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 11 THR A  31
ILE A  26
LEU A  49
ILE A   8
VAL A  72
 None
 1.24A 3a51A-2ko1A:
undetectable		 3a51A-2ko1A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 12 CYH A  47
THR A  35
ILE A  26
THR A  19
ASN A  39
 None
 1.21A 3ddyA-2ko1A:
undetectable		 3ddyA-2ko1A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 10 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.32A 3eqmA-2ko1A:
undetectable		 3eqmA-2ko1A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 10 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.27A 4kq8A-2ko1A:
undetectable		 4kq8A-2ko1A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 11 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.32A 5jkwA-2ko1A:
undetectable		 5jkwA-2ko1A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL6_A_ASDA601_1
(AROMATASE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 9 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.31A 5jl6A-2ko1A:
0.0		 5jl6A-2ko1A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 10 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.30A 5jl7A-2ko1A:
0.0		 5jl7A-2ko1A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL9_A_ASDA601_1
(AROMATASE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		5 / 9 ARG A  77
ILE A   8
ILE A  26
THR A  31
VAL A  53
 None
 1.34A 5jl9A-2ko1A:
undetectable		 5jl9A-2ko1A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		4 / 5 THR A  46
THR A  35
HIS A  83
LEU A  78
 None
 1.35A 6aphA-2ko1A:
undetectable		 6aphA-2ko1A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		4 / 5 THR A  46
THR A  35
HIS A  83
LEU A  78
 None
 1.35A 6gbnB-2ko1A:
undetectable		 6gbnB-2ko1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 2ko1 GTP
PYROPHOSPHOKINASE
(Chlorobaculum
tepidum) 		4 / 6 THR A  46
LEU A  38
THR A  74
LEU A  49
 None
 1.22A 6mvxA-2ko1A:
undetectable
6mvxB-2ko1A:
undetectable
6mvxC-2ko1A:
undetectable		 6mvxA-2ko1A:
14.04
6mvxB-2ko1A:
14.04
6mvxC-2ko1A:
14.04