SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2koj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2koj PARTITIONING
DEFECTIVE 3 HOMOLOG
(Mus
musculus) 		6 / 11 GLY A 472
ALA A 499
ASP A 502
ILE A 462
ILE A 475
ILE A 493
 None
 1.45A 1sdvB-2kojA:
undetectable		 1sdvB-2kojA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2koj PARTITIONING
DEFECTIVE 3 HOMOLOG
(Mus
musculus) 		4 / 7 LEU A 494
ILE A 488
VAL A 528
LEU A 531
 None
 0.71A 3r9vA-2kojA:
undetectable
3r9vB-2kojA:
undetectable		 3r9vA-2kojA:
19.26
3r9vB-2kojA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2koj PARTITIONING
DEFECTIVE 3 HOMOLOG
(Mus
musculus) 		5 / 11 GLY A 484
GLY A 483
THR A 481
VAL A 527
ASP A 518
 None
 1.11A 4pghA-2kojA:
undetectable		 4pghA-2kojA:
15.73