SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kpt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 LEU A 164
VAL A  79
GLY A 169
LEU A 117
 None
 0.94A 1jlbA-2kptA:
undetectable		 1jlbA-2kptA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.89A 1rxcB-2kptA:
undetectable		 1rxcB-2kptA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.89A 1rxcK-2kptA:
undetectable		 1rxcK-2kptA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 LEU A 164
VAL A  79
GLY A 169
LEU A 117
 None
 1.03A 1s1xA-2kptA:
undetectable		 1s1xA-2kptA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		5 / 12 ALA A  75
ILE A  76
ALA A 148
LEU A 121
ILE A 130
 None
 1.00A 2h42B-2kptA:
undetectable		 2h42B-2kptA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.86A 4e1vA-2kptA:
undetectable		 4e1vA-2kptA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.87A 4e1vC-2kptA:
undetectable		 4e1vC-2kptA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.86A 4e1vE-2kptA:
undetectable		 4e1vE-2kptA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 THR A 134
GLY A 132
GLN A 105
VAL A 116
 None
 0.81A 4e1vG-2kptA:
undetectable		 4e1vG-2kptA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 2kpt PUTATIVE SECRETED
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 GLU A 125
PRO A 100
GLY A  97
ASP A  99
 None
 1.05A 5kgpB-2kptA:
undetectable		 5kgpB-2kptA:
17.38