SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kpw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2kpw LAMIN-B1
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  78
TRP A  72
 None
 0.92A 1gmkA-2kpwA:
undetectable
1gmkB-2kpwA:
undetectable		 1gmkA-2kpwA:
4.92
1gmkB-2kpwA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2kpw LAMIN-B1
(Homo
sapiens) 		3 / 3 ALA A  80
VAL A  78
TRP A  72
 None
 0.95A 1gmkC-2kpwA:
undetectable
1gmkD-2kpwA:
undetectable		 1gmkC-2kpwA:
4.92
1gmkD-2kpwA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2kpw LAMIN-B1
(Homo
sapiens) 		4 / 8 GLY A  95
ASP A  21
ILE A  20
VAL A 100
 None
 0.80A 3fi0I-2kpwA:
undetectable		 3fi0I-2kpwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2kpw LAMIN-B1
(Homo
sapiens) 		3 / 3 HIS A   6
HIS A   4
HIS A   3
 None
 0.91A 5oexA-2kpwA:
undetectable		 5oexA-2kpwA:
14.78