SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2kqk NIFU-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 109
GLY A  30
SER A 123
ALA A 116
ALA A 119
 None
 1.07A 2br4C-2kqkA:
undetectable		 2br4C-2kqkA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2kqk NIFU-LIKE PROTEIN
(Escherichia
coli) 		4 / 5 LEU A  99
ALA A  68
ILE A  67
SER A  70
 None
 0.95A 2othA-2kqkA:
undetectable		 2othA-2kqkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 2kqk NIFU-LIKE PROTEIN
(Escherichia
coli) 		5 / 12 GLY A  38
ILE A 108
ILE A  67
PRO A 100
VAL A 102
 None
 0.90A 3nduA-2kqkA:
undetectable		 3nduA-2kqkA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2kqk NIFU-LIKE PROTEIN
(Escherichia
coli) 		3 / 3 ASP A  24
ASN A  26
ASP A  49
 None
 0.78A 5vopA-2kqkA:
undetectable		 5vopA-2kqkA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2kqk NIFU-LIKE PROTEIN
(Escherichia
coli) 		3 / 3 ASP A  24
ASN A  26
ASP A  49
 None
 0.82A 5vopB-2kqkA:
undetectable		 5vopB-2kqkA:
18.86