SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1
(Homo
sapiens) 		4 / 7 ARG A 309
PHE A 343
ILE A 300
ASN A 303
 None
 1.03A 2zseA-2kr0A:
undetectable		 2zseA-2kr0A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1
(Homo
sapiens) 		5 / 12 LEU A 347
ALA A 345
LEU A 310
LEU A 340
MET A 356
 None
 1.16A 3erdA-2kr0A:
undetectable		 3erdA-2kr0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1
(Homo
sapiens) 		5 / 12 LEU A 347
ALA A 345
LEU A 310
LEU A 340
MET A 356
 None
 1.12A 3hm1A-2kr0A:
undetectable		 3hm1A-2kr0A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1
(Homo
sapiens) 		4 / 5 LEU A 288
GLY A 341
MET A 297
PHE A 377
 None
 1.25A 3uq6B-2kr0A:
undetectable		 3uq6B-2kr0A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1
(Homo
sapiens) 		4 / 7 GLN A 157
LEU A 156
ALA A 149
LEU A 150
 None
 1.11A 5nwvA-2kr0A:
undetectable		 5nwvA-2kr0A:
5.11