SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2krr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 2krr NUCLEOLIN
(Homo
sapiens) 		5 / 12 LEU A  96
ALA A  98
ILE A 132
GLU A 144
PHE A 114
 None
 1.14A 3axtA-2krrA:
undetectable		 3axtA-2krrA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2krr NUCLEOLIN
(Homo
sapiens) 		4 / 6 GLU A  90
TYR A 164
GLU A 140
GLU A 144
 None
 1.40A 4r87H-2krrA:
undetectable		 4r87H-2krrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2krr NUCLEOLIN
(Homo
sapiens) 		4 / 8 GLU A 109
GLU A 112
VAL A 113
GLY A 157
 None
 0.98A 5sxtA-2krrA:
undetectable		 5sxtA-2krrA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2krr NUCLEOLIN
(Homo
sapiens) 		4 / 8 GLU A 109
GLU A 112
VAL A 113
GLY A 157
 None
 0.91A 5syjB-2krrA:
undetectable		 5syjB-2krrA:
13.31