SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2krt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
2krt CONSERVED
HYPOTHETICAL
MEMBRANE LIPOPROTEIN

(Ureaplasma
parvum)
5 / 9 LEU A  26
ILE A  42
PHE A  24
LEU A  86
ILE A  65
None
0.96A 2f7aB-2krtA:
undetectable
2f7aB-2krtA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)
2krt CONSERVED
HYPOTHETICAL
MEMBRANE LIPOPROTEIN

(Ureaplasma
parvum)
3 / 3 GLU A 115
HIS A 118
HIS A 119
None
0.87A 3co4A-2krtA:
undetectable
3co4A-2krtA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)
2krt CONSERVED
HYPOTHETICAL
MEMBRANE LIPOPROTEIN

(Ureaplasma
parvum)
5 / 12 LEU A  18
LEU A  86
TYR A  34
PHE A  68
LEU A  26
None
1.35A 3gwuA-2krtA:
undetectable
3gwuA-2krtA:
12.72