SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ks6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 8 SER A  51
ARG A  82
PHE A  54
ASN A  49
 None
 1.30A 1rs6B-2ks6A:
undetectable		 1rs6B-2ks6A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  66
GLU A  55
LEU A  86
 None
 0.62A 1v8bA-2ks6A:
4.7		 1v8bA-2ks6A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  66
GLU A  55
LEU A  86
 None
 0.62A 1v8bB-2ks6A:
4.7		 1v8bB-2ks6A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 6 GLY A  76
ILE A 106
ILE A  94
ASP A  73
 None
 0.97A 3a7eA-2ks6A:
undetectable		 3a7eA-2ks6A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 167
ALA A 162
ARG A 173
ILE A 169
GLU A  33
 None
 1.24A 4azsA-2ks6A:
2.6		 4azsA-2ks6A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 171
TYR A  37
VAL A 136
ILE A 114
PHE A  30
 None
 1.14A 4fglA-2ks6A:
4.6
4fglB-2ks6A:
4.7		 4fglA-2ks6A:
23.41
4fglB-2ks6A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ks6 UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		5 / 12 CYH A  12
SER A 115
LEU A 168
ILE A  44
TYR A 200
 None
 1.46A 6md4A-2ks6A:
undetectable		 6md4A-2ks6A:
14.43