SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ksb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 ARG A 340
GLY A 315
HIS A 318
ILE A  57
ASN A  68
 None
 1.35A 3a25A-2ksbA:
undetectable		 3a25A-2ksbA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 161
ILE A 182
PHE A 264
LEU A 269
ILE A 198
 None
 1.14A 3cd2A-2ksbA:
undetectable		 3cd2A-2ksbA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 252
MET A 249
LEU A 308
CYH A 306
ILE A  56
 None
 1.39A 3mnoA-2ksbA:
undetectable		 3mnoA-2ksbA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 252
MET A 249
LEU A 308
CYH A 306
ILE A  56
 None
 1.38A 3mnpA-2ksbA:
undetectable		 3mnpA-2ksbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		4 / 7 MET A 299
THR A  45
THR A  40
VAL A  44
 None
 1.00A 4ik7A-2ksbA:
undetectable		 4ik7A-2ksbA:
16.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HLO_A_GBQA1501_0
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		6 / 12 TYR A 196
THR A 201
TRP A 261
PHE A 264
HIS A 265
MET A 295
 None
 1.05A 6hloA-2ksbA:
25.8		 6hloA-2ksbA:
62.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 ILE A 113
THR A 201
TRP A 261
HIS A 265
PRO A 271
 None
 1.17A 6hlpA-2ksbA:
25.9		 6hlpA-2ksbA:
62.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 PRO A 112
ILE A 113
TRP A 261
HIS A 265
PRO A 271
 None
 0.92A 6hlpA-2ksbA:
25.9		 6hlpA-2ksbA:
62.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 200
THR A 201
ILE A 204
HIS A 265
PHE A 264
 None
 1.13A 6hlpA-2ksbA:
25.9		 6hlpA-2ksbA:
62.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 TYR A 196
THR A 201
ILE A 204
HIS A 265
MET A 295
 None
 0.90A 6j20A-2ksbA:
26.3		 6j20A-2ksbA:
74.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2ksb SUBSTANCE-P RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 116
TYR A 196
THR A 201
PHE A 264
HIS A 265
 None
 0.96A 6j20A-2ksbA:
26.3		 6j20A-2ksbA:
74.38