SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ktr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 2ktr SEQUESTOSOME-1
(Rattus
norvegicus) 		5 / 11 LEU A  81
GLU A  80
VAL A  73
ALA A  74
LEU A  72
 None
 1.25A 2c12F-2ktrA:
undetectable		 2c12F-2ktrA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 2ktr SEQUESTOSOME-1
(Rattus
norvegicus) 		5 / 11 LEU B 281
GLU B 280
VAL B 273
ALA B 274
LEU B 272
 None
 1.25A 2c12F-2ktrB:
undetectable		 2c12F-2ktrB:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 2ktr SEQUESTOSOME-1
(Rattus
norvegicus) 		3 / 3 ARG A  94
ARG A  66
ILE A  92
 None
 0.94A 4b7qA-2ktrA:
undetectable		 4b7qA-2ktrA:
13.16