SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 2kua BCL-2-LIKE PROTEIN
10
(Mus
musculus) 		3 / 3 ASP A   3
GLU A  10
ARG A 142
 None
 0.85A 1wopA-2kuaA:
undetectable		 1wopA-2kuaA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 2kua BCL-2-LIKE PROTEIN
10
(Mus
musculus) 		3 / 3 ARG A 113
LEU A 115
THR A  29
 None
 0.78A 3oxcA-2kuaA:
undetectable		 3oxcA-2kuaA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2kua BCL-2-LIKE PROTEIN
10
(Mus
musculus) 		3 / 3 THR A  35
SER A  36
ARG A  14
 None
 0.82A 3phnA-2kuaA:
undetectable		 3phnA-2kuaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2kua BCL-2-LIKE PROTEIN
10
(Mus
musculus) 		5 / 12 PHE A 158
LEU A  41
GLY A 149
LEU A 148
VAL A  91
 None
 1.12A 4wnwB-2kuaA:
undetectable		 4wnwB-2kuaA:
18.12