SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kuc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 2kuc PUTATIVE
DISULPHIDE-ISOMERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 103
GLY A  37
ASP A 105
VAL A 113
LEU A 100
 None
 1.07A 3m6wA-2kucA:
undetectable		 3m6wA-2kucA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2kuc PUTATIVE
DISULPHIDE-ISOMERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TRP A  35
LEU A  42
PRO A  38
LEU A 100
 None
 1.00A 5eshA-2kucA:
undetectable		 5eshA-2kucA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2kuc PUTATIVE
DISULPHIDE-ISOMERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A  62
ARG A   9
GLU A  23
ARG A  19
 None
 1.08A 6b8kA-2kucA:
undetectable		 6b8kA-2kucA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 2kuc PUTATIVE
DISULPHIDE-ISOMERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A  62
ARG A   9
GLU A  23
ARG A  19
 None
 1.09A 6b94A-2kucA:
undetectable		 6b94A-2kucA:
19.70