SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kvb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2kvb CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR
(Bos
taurus) 		3 / 3 ASN A 626
ALA A 613
LYS A 610
 None
 0.83A 3runA-2kvbA:
undetectable		 3runA-2kvbA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2kvb CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR
(Bos
taurus) 		4 / 4 GLY A 641
GLY A 656
THR A 689
LEU A 671
 None
 0.80A 3si7C-2kvbA:
undetectable
3si7D-2kvbA:
undetectable		 3si7C-2kvbA:
16.97
3si7D-2kvbA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2kvb CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR
(Bos
taurus) 		3 / 3 SER A 648
LYS A 620
SER A 646
 None
 0.73A 6az3P-2kvbA:
undetectable		 6az3P-2kvbA:
16.89